XNAS 05 May, 2026 4:00 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Mar 2026 | 2,090 | 71,048 | - | - | Employee Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 3.26 per share. | 06 Mar 2026 | 2,090 | 173,999 | - | 3.3 | 6,813 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.85 per share. | 06 Mar 2026 | 2,090 | 176,089 | - | 1.9 | 3,867 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.85 per share. | 27 Feb 2026 | 9,406 | 183,405 | - | 1.8 | 17,401 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 9,406 | 73,138 | - | - | Employee Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 3.01 per share. | 27 Feb 2026 | 9,406 | 173,999 | - | 3.0 | 28,311 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jan 2026 | 2,671 | 82,544 | - | - | Employee Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Jan 2026 | 15,085 | 85,215 | - | - | Employee Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 26 Jan 2026 | 2,671 | 173,999 | - | 3.0 | 8,017 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.85 per share. | 26 Jan 2026 | 2,671 | 176,670 | - | 1.8 | 4,941 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 3.00 per share. | 26 Jan 2026 | 15,085 | 173,999 | - | 3.0 | 45,263 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.85 per share. | 26 Jan 2026 | 15,085 | 189,084 | - | 1.8 | 27,907 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.84 per share. | 21 Jan 2026 | 1,054 | 179,632 | - | 1.8 | 1,939 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.81 per share. | 21 Jan 2026 | 2,247 | 180,686 | - | 1.8 | 4,063 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.90 per share. | 21 Jan 2026 | 5,633 | 173,999 | - | 1.9 | 10,718 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.81 per share. | 21 Jan 2026 | 9,346 | 883,964 | - | 1.8 | 16,927 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.88 per share. | 21 Jan 2026 | 2,689 | 881,275 | - | 1.9 | 5,066 | Common Stock |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 21 Jan 2026 | 895 | 255,371 | - | 1.8 | 1,629 | Common Stock |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.80 per share. | 21 Jan 2026 | 2,331 | 256,266 | - | 1.8 | 4,204 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.81 per share. | 21 Jan 2026 | 2,315 | 205,554 | - | 1.8 | 4,181 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.84 per share. | 21 Jan 2026 | 462 | 205,092 | - | 1.8 | 850 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2026 | 299,800 | 893,310 | - | 0 | Common Stock | |
| Daniel O'Connell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jan 2026 | 450,000 | 450,000 | - | - | Employee Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 99,133 | 182,933 | - | 0 | Common Stock | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 148,700 | 148,700 | - | - | Employee Stock Option (right to buy) | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 99,133 | 258,597 | - | 0 | Common Stock | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 148,700 | 148,700 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 126,900 | 126,900 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 84,600 | 207,869 | - | 0 | Common Stock | |
| James J. Doherty | President and CDO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 250,300 | 250,300 | - | - | Employee Stock Option (right to buy) | |
| James J. Doherty | President and CDO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 166,867 | 220,900 | - | 0 | Common Stock | |
| Amy Schacterle | Chief Regulatory Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 126,900 | 126,900 | - | - | Employee Stock Option (right to buy) | |
| Amy Schacterle | Chief Regulatory Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2026 | 84,600 | 92,303 | - | 0 | Common Stock | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 08 Jan 2026 | 6,819 | 127,640 | - | 1.8 | 12,379 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.71 per share. | 08 Jan 2026 | 8,548 | 83,800 | - | 1.7 | 14,658 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.76 per share. | 08 Jan 2026 | 5,200 | 92,348 | - | 1.8 | 9,169 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 08 Jan 2026 | 30,092 | 97,548 | - | 1.8 | 54,867 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 08 Jan 2026 | 8,143 | 611,839 | - | 1.8 | 14,815 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.73 per share. | 08 Jan 2026 | 5,388 | 593,510 | - | 1.7 | 9,307 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.76 per share. | 08 Jan 2026 | 12,941 | 598,898 | - | 1.8 | 22,832 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.86 per share. | 08 Jan 2026 | 3,530 | 123,269 | - | 1.9 | 6,562 | Common Stock |
| James J. Doherty | President and CDO | Sale of securities on an exchange or to another person at price $ 1.99 per share. | 07 Jan 2026 | 1,700 | 60,500 | - | 2.0 | 3,379 | Common Stock |
| James J. Doherty | President and CDO | Sale of securities on an exchange or to another person at price $ 1.82 per share. | 07 Jan 2026 | 6,467 | 54,033 | - | 1.8 | 11,769 | Common Stock |
| Amy Schacterle | Chief Regulatory Officer | Sale of securities on an exchange or to another person at price $ 1.98 per share. | 07 Jan 2026 | 1,097 | 7,703 | - | 2.0 | 2,176 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 3,801 | 146,229 | - | 2.0 | 7,477 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 7,097 | 150,030 | - | 2.0 | 13,961 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.96 per share. | 05 Jan 2026 | 4,000 | 157,127 | - | 2.0 | 7,838 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.99 per share. | 05 Jan 2026 | 10,070 | 134,459 | - | 2.0 | 20,035 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.99 per share. | 05 Jan 2026 | 1,700 | 144,529 | - | 2.0 | 3,379 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 4,649 | 662,839 | - | 2.0 | 9,163 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 5,102 | 657,737 | - | 2.0 | 10,032 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.99 per share. | 05 Jan 2026 | 37,755 | 619,982 | - | 2.0 | 74,981 | Common Stock |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 6,834 | 159,464 | - | 2.0 | 13,442 | Common Stock |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.96 per share. | 05 Jan 2026 | 4,000 | 166,298 | - | 2.0 | 7,835 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.99 per share. | 05 Jan 2026 | 1,700 | 126,799 | - | 2.0 | 3,378 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.97 per share. | 05 Jan 2026 | 3,618 | 128,499 | - | 2.0 | 7,114 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.96 per share. | 05 Jan 2026 | 4,000 | 132,117 | - | 2.0 | 7,832 | Common Stock |
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 12,800 | - | 0 | Common Stock | |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 12,800 | - | 0 | Common Stock | |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 12,800 | - | 0 | Common Stock | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 185,124 | - | 0 | Common Stock | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 19,050 | - | 0 | Common Stock | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 12,800 | 12,800 | - | 0 | Common Stock | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jun 2025 | 19,500 | 19,500 | - | - | Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.59 per share. | 21 Jan 2025 | 3,418 | 161,127 | - | 1.6 | 5,435 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.59 per share. | 21 Jan 2025 | 12,619 | 667,488 | - | 1.6 | 20,102 | Common Stock |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.59 per share. | 21 Jan 2025 | 3,219 | 170,298 | - | 1.6 | 5,118 | Common Stock |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.61 per share. | 21 Jan 2025 | 2,914 | 136,117 | - | 1.6 | 4,692 | Common Stock |
| James J. Doherty | President and CDO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 93,300 | 93,300 | - | - | Employee Stock Option (right to buy) | |
| James J. Doherty | President and CDO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 62,600 | 62,600 | - | 0 | Common Stock | |
| Amy Schacterle | Chief Regulatory Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 13,200 | 13,200 | - | - | Employee Stock Option (right to buy) | |
| Amy Schacterle | Chief Regulatory Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jan 2025 | 8,800 | 8,800 | - | 0 | Common Stock | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 1.84 per share. | 03 Jan 2025 | 11,122 | 97,745 | - | 1.8 | 20,506 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 66,800 | 164,545 | - | 0 | Common Stock | |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 100,300 | 100,300 | - | - | Employee Stock Option (right to buy) | |
| Daniel O'Connell | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 1.84 per share. | 03 Jan 2025 | 47,778 | 454,707 | - | 1.8 | 87,873 | Common Stock |
| Daniel O'Connell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 338,000 | 338,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel O'Connell | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 225,400 | 680,107 | - | 0 | Common Stock | |
| Eric Siemers | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 1.85 per share. | 03 Jan 2025 | 10,859 | 106,717 | - | 1.8 | 20,047 | Common Stock |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 66,800 | 173,517 | - | 0 | Common Stock | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 100,300 | 100,300 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 74,700 | 74,700 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2025 | 49,800 | 139,031 | - | 0 | Common Stock | |
| Russell Barton | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 1.86 per share. | 03 Jan 2025 | 7,636 | 89,231 | - | 1.9 | 14,225 | Common Stock |
| Amy Schacterle | Chief Regulatory Officer | 05 Nov 2024 | 340,000 | 340,000 | - | - | Employee Stock Option (right to buy) | ||
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jun 2024 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Doherty J. James | President and CDO | 01 Feb 2024 | 601,000 | 601,000 | - | - | Employee Stock Option (right to buy) | ||
| O'Connell Daniel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.47 per share. | 19 Jan 2024 | 15,200 | 502,485 | - | 3.5 | 52,753 | Common Stock |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | Sale of securities on an exchange or to another person at price $ 3.48 per share. | 19 Jan 2024 | 8,933 | 108,867 | - | 3.5 | 31,048 | Common Stock |
| Siemers Eric | Chief Medical Officer | Sale of securities on an exchange or to another person at price $ 3.71 per share. | 18 Jan 2024 | 3,124 | 117,576 | - | 3.7 | 11,604 | Common Stock |
| Barton Russell | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 3.73 per share. | 18 Jan 2024 | 2,833 | 96,867 | - | 3.7 | 10,555 | Common Stock |
| M. Derek Meisner | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 137,000 | 137,000 | - | - | Employee Stock Option (right to buy) | |
| Siemers Eric | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 94,000 | 120,700 | - | 0 | Common Stock | |
| Meisner Derek M. | Chief Legal Officer & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 91,000 | 117,800 | - | 0 | Common Stock | |
| Daniel O'Connell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 401,000 | 517,685 | - | 0 | Common Stock | |
| Barton Russell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 73,000 | 99,700 | - | 0 | Common Stock | |
| Siemers Eric | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 141,000 | 141,000 | - | - | Employee Stock Option (right to buy) | |
| O'Connell Daniel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 602,000 | 602,000 | - | - | Employee Stock Option (right to buy) | |
| Barton Russell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 110,000 | 110,000 | - | - | Employee Stock Option (right to buy) | |
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 Jun 2023 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Derek M. Meisner | Chief Legal Office & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 26,800 | 26,800 | - | 0 | Common Stock | |
| Derek M. Meisner | Chief Legal Office & Corp Sec | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 120,800 | 120,800 | - | - | Employee Stock Option (right to buy) | |
| Daniel O'Connell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 114,000 | 116,685 | - | 0 | Common Stock | |
| Daniel O'Connell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 472,500 | 472,500 | - | - | Employee Stock Option (right to buy) | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 26,700 | 26,700 | - | 0 | Common Stock | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 120,200 | 120,200 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 120,200 | 120,200 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 26,700 | 26,700 | - | 0 | Common Stock | |
| Derrell D. Porter | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2023 | 50,000 | 50,000 | - | - | Stock Option Grant (right to buy) | |
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Jeffrey Sevigny | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2022 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Kimberlee Cobleigh Drapkin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2022 | 50,000 | 50,000 | - | - | Stock Option Grant (right to buy) | |
| Daniel O'Connell | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 455,000 | 455,000 | - | - | Employee Stock Option (right to buy) | |
| Eric Siemers | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 90,000 | 90,000 | - | - | Employee Stock Option (right to buy) | |
| Russell Barton | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jan 2022 | 135,000 | 135,000 | - | - | Employee Stock Option (right to buy) | |
| Daniel O'Connell | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Nov 2021 | 1,118 | 0 | - | - | Stock Option (Right to Buy) | |
| Daniel O'Connell | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.47 per share. | 30 Nov 2021 | 1,118 | 2,685 | - | 4.5 | 4,997 | Common Stock |
| Sean Stalfort | Director | Purchase of securities on an exchange or from another person at price $ 16.00 per share. | 06 Jul 2021 | 35,000 | 172,324 | - | 16 | 560,000 | Common Stock |
| Sean Stalfort | Director | 06 Jul 2021 | 130,180 | 137,324 | - | - | Common Stock | ||
| Sean Stalfort | Director | 06 Jul 2021 | 130,180 | 0 | - | - | Series A-1 Preferred | ||
| Sean Stalfort | Director | 06 Jul 2021 | 131,595 | 131,595 | - | - | Common Stock | ||
| Sean Stalfort | Director | 06 Jul 2021 | 131,595 | 0 | - | - | Series B Preferred | ||
| Daniel O'Connell | Director, President and CEO | 06 Jul 2021 | 35 | 1,577 | - | 4.5 | 156 | Common Stock | |
| Daniel O'Connell | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2021 | 35 | 0 | - | - | Warrant (Right to Buy) | |
| Daniel O'Connell | Director, President and CEO | 06 Jul 2021 | 123 | 0 | - | - | Series A Preferred Stock | ||
| Daniel O'Connell | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.00 per share. | 06 Jul 2021 | 10 | 1,567 | - | 16 | 160 | Common Stock |
| Daniel O'Connell | Director, President and CEO | 06 Jul 2021 | 123 | 1,542 | - | - | Common Stock | ||
| Nathan B. Fountain | Director | Purchase of securities on an exchange or from another person at price $ 16.00 per share. | 06 Jul 2021 | 6,250 | 6,250 | - | 16 | 100,000 | Common Stock |
| Nathan B. Fountain | Director | Purchase of securities on an exchange or from another person at price $ 16.00 per share. | 06 Jul 2021 | 6,250 | 6,250 | - | 16 | 100,000 | Common Stock |
| Jeffrey L. Ives | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy) | |
| Sean Stalfort | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Sevigny | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy) | |
| Nathan B. Fountain | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy) | |
| Laura Stoppel | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2021 | 34,000 | 34,000 | - | - | Stock Option (Right to Buy) |